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Laboratory calculation · MC-002

Acute/baseline tryptase change (20% + 2)

Support retrospective confirmation of mast-cell activation

In development — calculation unavailable

This catalogue entry is not an approved clinical calculator. Its formula, interpretation and licensing have not been signed off. Do not use it to guide patient care.

Intended population or setting
Suspected anaphylaxis with paired acute and baseline tryptase
Important cautions
Normal tryptase does not exclude anaphylaxis; never delay epinephrine or acute care
Specialities
Allergy and Clinical Immunology · Anesthesiology · Emergency Medicine · Pathology
Preferred source/version
20% + 2 rule; display collection timing
Review status
Draft · Practice parameter verified

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When released, this tool will support but not replace professional clinical judgement. Check current local guidance and the original source before use.