3 min read
Atenolol Outperformed Bisoprolol After MI Without Recorded Heart Failure
A French observational study found fewer major cardiovascular events with atenolol over two years—but no statistically significant mortality difference.
Updates in Medicine
Research
Selected clinical studies, interpreted with the outcomes, limitations and context that matter.
5 min read
Single-Infusion PCSK9 Base Editing Produces Substantial LDL-C Lowering Sustained Beyond One Year
Phase 1 data suggest that one-time in-vivo PCSK9 editing can produce large and durable LDL-C reductions, although long-term safety and cardiovascular benefit remain uncertain.
6 min read
Alcohol Intake and Lifetime Health Risk: No Net Protective Effect at Low Consumption
A US cause-specific modelling analysis estimates how weekly alcohol intake and drinking pattern relate to lifetime mortality, morbidity and injury risk.
7 min read
Met-HeFT 2026: Metformin Failed to Reduce Cardiovascular Events in HFrEF
The randomised trial tested whether metformin provides cardiovascular protection beyond glucose lowering in HFrEF.