
Systemic lupus erythematosus in 2026
The GLADEL–PANLAR update separates mild skin and joint disease from moderate-to-severe disease and sets out combination regimens for proliferative lupus nephritis.
Updates in Medicine
Updates in Medicine articles that explain guidelines for everyday clinical practice.

The GLADEL–PANLAR update separates mild skin and joint disease from moderate-to-severe disease and sets out combination regimens for proliferative lupus nephritis.

A practical reading of the 2026 AustrAIHANZ consensus on confirming immune haemolysis, urgent transfusion and early steroid-sparing treatment for warm AIHA.

What changed in measured tidal volume, adult ventilation bag size and routine fluid use—and the exceptions and evidence limits that matter.

Putting the iLATAM-AP guideline into practice: reassessed fluids, early feeding, selective ERCP, infection-directed antibiotics and a step-up approach to complications.

A practical guide to outpatient suitability, admission, recognition of deterioration and escalation using the 2026 AHA/ACC multisociety framework.

The new shared ACLF definition, organ-dysfunction grades and bedside priorities for recognising deterioration, treating precipitants and assessing transplant candidacy.

How the Austrian radiology–nephrology consensus approaches iodinated contrast, hydration, medication review and low-risk gadolinium agents.

A practical reading of the HFSA scientific statement: assess congestion and perfusion, identify the cause and tailor treatment to right ventricular physiology.

An evidence-based clinical guide to prescribing exercise for cardiovascular prevention, coronary artery disease, heart failure, hypertension and other cardiovascular conditions.

New proposals for kidney and cardiovascular protection, alongside established CKD treatment. Public-review draft—not a final guideline.

Individualising antiplatelet selection, duration and de-escalation to balance thrombotic protection against bleeding risk.

A practical summary of prevention in cirrhosis, including portal hypertension, encephalopathy, infections, HCC surveillance, vaccination, nutrition and bone health.

A practical guide to the 2026 consensus: consider organ-protective treatment early, then individualise care around cardiovascular and kidney risk, weight and glycaemic goals.

Assess ASCVD risk, set an appropriate LDL-C goal, intensify treatment when needed and sustain LDL-C lowering over time.

Putting the 2026 ACC Scientific Statement into practice: focus on food quality, healthy substitutions and sustainable dietary patterns.

A practical approach to selecting noninvasive respiratory support, recognising when intubation is needed and reassessing early to avoid delayed escalation.

EASL–EASD–EASO guidance in practice: selecting eligible adults with non-cirrhotic F2–F3 MASH, choosing between resmetirom and semaglutide, and monitoring response and safety.

A practical approach to universal Lp(a) measurement, cardiovascular risk interpretation and management based on the 2026 National Lipid Association Lipid Simplified review.

A practical guide to recognising suspected TTP, collecting a pre-treatment ADAMTS13 sample, interpreting activity and antibody results, and monitoring after diagnosis.

A practical approach to diagnosis, multimodality imaging, antimicrobial treatment, surgical timing and post-operative care.

A practical guide to confirming malaria, assessing severity, selecting treatment, and responding safely in special populations.

From initial severity assessment to bronchodilator treatment, escalation, discharge and prevention of recurrent exacerbations.

A practical guide to treating ESBL-E, AmpC-E, CRE, DTR Pseudomonas aeruginosa, CRAB and Stenotrophomonas maltophilia.

What clinicians need to know about diagnosing COPD, the revised ABE assessment, initial and follow-up treatment, exacerbation prevention, biologic therapy and acute exacerbation management.

A practical guide to classification, diagnosis, foundational therapy, decompensated HF, devices, comorbidities, advanced HF and follow-up.

A mechanism-based framework for distinguishing myocardial infarction from myocardial injury and identifying its cause.

A practical approach to rehabilitation timing, exercise, mental health and long-term recovery.

A practical pharmacologic approach for adult migraine prevention

A pathophysiology-based definition centred on three essential diagnostic pillars.

A practical approach to managing chronic kidney disease and cardiovascular disease together.