Original research
Family Medicine and Primary Care
Original research relevant to this speciality, newest first.
- Financial incentives improve smoking cessation among people referred for lung cancer screening
JAMA
Randomized trial. Six-month sustained abstinence was 8.8% with free pharmacotherapy plus incentives versus 4.3% with usual care. - Navigation, reminders and automatic referral improve colonoscopy completion after a positive stool test
JAMA Internal Medicine
Systematic review/meta-analysis, 21 studies. Several practical interventions improved follow-up; effects varied across studies. - Combining nutritional supplements with routine immunization increases measles vaccine uptake
Nature Medicine
NutriVax cluster-randomized trial, northern Nigeria. Card-verified first-dose coverage improved by approximately 20 percentage points relative to control over time. - Longer opioid-use-disorder treatment around childbirth is associated with fewer postpartum overdoses or deaths
JAMA Network Open
Cohort study, 9,360 pregnancies. Longer medication coverage was associated with lower risk through one year postpartum; this was not randomized evidence. - Supervised exercise improves persistent knee symptoms after ACL reconstruction
Annals of Internal Medicine
Randomized trial, 184 young adults. Modest additional improvement at four months; differences narrowed at twelve months, with no demonstrated cartilage benefit. - Facilitated cascade testing increases BRCA testing among at-risk relatives
Journal of Clinical Oncology
Cluster-randomized trial. Six-month testing uptake: 73.2% with navigation versus 50.7% with standard care. - Fasting beyond 12 hours adds little to routine laboratory testing
JAMA Internal Medicine
Large cross-sectional analysis. Supports test-specific fasting requirements; it does not mean fasting is unnecessary for every test. - Short oral corticosteroid courses were associated with serious adverse events in adults with type 2 diabetes.
JAMA Network Open
Self-controlled study of 36,048 patients. Increased gastrointestinal bleeding, pneumonia and heart failure during days 6–30 after initiation. - Whole grains modestly improved LDL cholesterol and other cardiometabolic risk factors.
European Heart Journal
- Atorvastatin reduced cardiovascular events in healthy adults aged ≥70, without improving disability-free survival.
NEJM